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Elevated systolic or diastolic pressure causes increased cardiovascular riskand the absolute risk increase per mmHg is greater at higher blood pressuresso that even modest reductions of severe hypertension can provide substantial benefitRelative risk reduction from blood pressure reduction is similar across populations with varying absolute riskso the absolute benefit is greater in patients who are at higher risk independent of their hypertensionfor examplepatients with diabetes or hyperlipidemiaand such patients would be expected to benefit from more aggressive treatment to a lower blood pressure goal.

If you are being treated for high blood pressurekeep using this medication even if you feel wellHigh blood pressure often has no symptomsYou may need to use blood pressure medication for the rest of your life.

A lower dose should be considered for patients with a history of hepatic impairmentThere is no therapeutic experience in patients with severe hepatic impairmentThereforelosartan is contraindicated in patients with severe hepatic impairmentsee sections 4.3 and 4.4

It is unknown if this drug passes into breast milkConsult your doctor before breast-feeding.

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